The Petasis reagent is also very air stable, and is commonly used in solution with toluene or THF. The Tebbe reagent and the Petasis reagent share a similar reaction mechanism. The active olefinating reagent, Cp 2 TiCH 2 , is generated in situ upon heating.
A direct synthesis of allenes by a traceless petasis reaction T1 - A direct synthesis of allenes by a traceless petasis reaction. AU - Mundal, Devon A. AU - Lutz, Kelly E. AU - Thomson, Regan J. PY - 2012/4/4. Y1 - 2012/4/4. N2 - A one-pot synthesis of allenes by the 2-nitrobenzenesulfonylhydrazide- mediated coupling of hydroxyaldehydes or ketones with alkynyl trifluoroborate salts is reported. Petasis three-component reactions for the synthesis of The Petasis three-component reaction (PR) of hydroxy aldehydes, amines and boronic acids is an important multi-component reaction for the synthesis of structurally diverse scaffolds and biologically interesting small molecules. traceless and four-component approaches. The excellent stereoselectivity, high yield and broad functional group
petasis | Sigma-Aldrich
A traceless isoprenylation method of non‐conjugated aldehydes is reported. Synthesis of the required N‐Boc‐N‐(1,1‐dimethylallyl)hydrazine precursor, as well as the N‐Boc‐N‐allylhydrazones are described. Optimisation reactions for the rearrangement were performed and the scope of … Publications | Thomson Research Group 8. Thomson, R. J. “(S)-4-(Phenylmethyl)-2-thiazolidinethione,” In The Electronic Encyclopedia of Reagents for Organic Synthesis, Wiley, 2007. [link] 7. Morrison
Traceless - trailer - YouTube
Traceless - trailer - YouTube Apr 04, 2016